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Subsequent biopsies reveal the proband had not progressed in terms of deposition

Figure 3 Dendritic cells recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) through Toll-like receptors (TLRs), thereby initiating an immune response (138), in COPD, dendritic cells are activated via TLR2, promoting the differentiation of Th17 cells and contributing to the development of emphysema

Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins

In this Review, we summarize the major environmental pollutants that are attracting wide-ranging concern and the molecular basis underlying their effects on the immune system